Coricidin is for Fuckers. - Nubblies.net Forums

ProfessorNumber · 10-19-2003, 12:05 AM

DXM, Coricidin, Robo-trippin, whatever you want to call it, is quite possibly the STUPIDEST drug of all times. I’ve noticed that the dangers of most drugs are over exaggerated, but when someone tells you that coricidin fries your brain, they aren’t kidding. You want to know what dissociatives such as DXM do to your brain?

1. Dissociatives activate neurons in the posterior cingulate cortex (PC) and retrosplenial cortex (RC). These overactive neurons pass along their excitation to "downstream" areas such as the hippocampus and olfactory areas.
There are two theories on why the PC and RC neurons get overexcited in the first place; either one, both, or neither could be true. One theory is that NMDA receptors are found on inhibitory GABA interneurons, and that when these receptors are blocked, these interneurons secrete less GABA, and thus excitatory pyramidal neurons that normally receive a lot of GABA inhibition are overexcited.
The other theory is that the PC and RC are less affected by NMDA blockade than the hippocampus (and related areas), and that these formations serve as feedback to the hippocampus and surrounding networks. As these limbic networks are inhibited, the PC and RC increase their output to compensate, resulting in overactivity.
2. The overactive cells begin to heat up, use up their energy supply generate toxic waste products, and/or let in too many calcium ions.
3. Regardless of the mechanism, or whether the mechanism is none of the above, the overactivity seems to cause intracellular organelles (notably mitochondria and endoplasmic reticulum) to malfunction.
4. The mitochondria probably lose their proton gradient and allow their innards to spill into the surrounding cell material, where they cause all sorts of trouble, possibly including forming free radicals which cause further damage to the cell. Another possibility is that the free radicals come first, and they cause damage to the mitochondria and other organelles. Mitochondrial damage can occur within 15 minutes of the drug dose, the endoplasmic reticulum is damaged 30 minutes, and in both cases gets worse as time progresses. The free radicals, basically, destroy everything in the cell like a rampant two-year-old on a spending spree through Toys-R-Us.
5. The cell responds to this damage with a protein called HSP70. This "heat shock" protein is made and activated when something (such as overheating, thus the name "heat shock protein" or HSP) is causing a cell to malfunction so badly as to be in danger of self-destructing, and its job is to turn the cell off until repairs can be made. Hopefully, the cell will get a lot of rest (about 24 hours) until it goes back to normal. At this point the problem is still reversible and the brain cells have not been permanently damaged.
6. If the cell continues to be overexcited, it eventually burns out completely as the increased temperature, disrupted ion gradient, hypoxia, calcium ions, free radicals, and/or buildup of waste products kill it. At this point, surrounding support cells called microglia are activated and come in and eat the cell (probably under the theory that if an infectious organism caused the cell death, it'd better be destroyed before the infection can spread). Source

For those of you who are too lazy to read that, it basically states that damage is done to your brain when certain cells overheat and rupture. Taking excessive doses of dissociatives make certain parts of your brain fry like the proverbial egg-on-the-frying-pan in the "This is Your Brain on Drugs" commercial.

Now, why is this relevant? Before I left Warsaw, I noticed that this “drug” was gaining a lot of popularity among stupid bitches. Why? Because of it’s easy availability, and quasi-legality. Personally I think it’s ridiculous that anyone would be so desperate to get “high” that they would stoop to using a fucking stupid drug like DXM. If you ever see someone using DXM/Coricidin, smack them on their fucking face.

Schroeder · 10-19-2003, 12:30 AM

Ooh, a chance to go role reversal.

Dear ProfessorNumber, Why do you try to push your ideals on others? Why don't you just let people do what they want? I mean, they are not hurting anyone but themselves. If they want to make themselves retarded, let them. I mean sometimes DXM is probably even helpful. If you had a brain tumor you could use DXM to kill the tumor. Yeah, DXM needs to be legalized more!

VOL · 10-19-2003, 12:44 AM

This drug is stupid and these girls taking it are probably only doing it for popularity. Same reason they all chew tabacco. It's just to say, "hey I'm doing a drug."

Saint DH · 10-19-2003, 04:06 AM

Yeah, alot of people at the highschool do that all the time now it seems. The only problem is, I don't even think the stupid bitches know that the drug they are doing is called DXM. They call it "Triple C's" because the name of the pills they take are called Coricidin Cold and Cough. Those people that do this drug, do it quite often, and they're going to have some serious brain damage.

I find it somewhat funny that people are so stupid as to take drugs that they really don't know anything about. If I was ever going to do a certain type of drug, I would research the fuck out of it, find out all the possible side effects, and possible things that could happen to me while on the drug. For instance, Coricidin can be lethal to certain types of people if they take too many of them...like the ammount that it would take to get fucked up off of them.

Man people are fucking stupid.

[ October 19, 2003, 02:08 AM: Message edited by: Dirty Harry ]

VOL · 10-19-2003, 01:14 PM

I might have missed it. Does this drug (triple c) give the user a high.

I mean what is the whole big thing. I was talking with a girl the other day who said that her and her friends took them. And they felt "good." What does that mean? Does this drug take immediate effect on the brain?

Alpha · 10-19-2003, 02:08 PM

PN, your wisdom finally shows it's glory.

Fuck all the stupid girls that do this, and all the guys for that matter.

Niger Angelus · 10-19-2003, 10:43 PM

I know a few girls that do it, one has quite the 'chunny fin', and yes; from what I have seen of them it does harm your brain.

VOL · 10-21-2003, 12:22 AM

Niger, VOL knows these girls as well

the_butcher · 10-21-2003, 01:58 AM

First of all, Schroeder, fuck you. You try to push your god-fearing, Jesus-loving bullshit on us all the time. Don't try to talk about pushing ideals on people you fucking hypocrite.

Second of all, VOL, they are taking the drug for popularity? Get your head out of your ass.

Lastly, I know people who have done this many a time and not been affected mentally. While I have never done it myself, I see no harm in letting other people do it. However, I wouldn't trust pills that I didn't know what's in them.

As for funny chin and her friends, fuck all those girls. They'd smoke cat shit if they thought it would get them high.

Schroeder · 10-21-2003, 02:08 AM

Tsk, tsk, Butcher. All I did was the same thing everyone always does to me.

the_butcher · 10-21-2003, 02:40 AM

So you took a first grade mentality, congratulations. If he punches me, I'll punch him back. Are you sure that's the way Jesus would want you to handle things? If I can remember right, he once said to turn the other cheek. What's that? Suprised I know some scripture? Yeh, I was forced to waste a lot of time with it during childhood, but being the intelligent human being I am, I grew up and realized how much of a waste it was. Maybe someday you will to. Then again, probably not.

Schroeder · 10-21-2003, 02:45 AM

Am I really wasting my time? If I do just die and rot in the ground, has having a religion really cost me anything? No, Butcher, it has not. Not a single thing. If I do end up being right, well then, things will be great. I've got nothing to lose, and everything to gain. Sounds pretty intelligent to me.

What about religion was a waste to you?

God also said an eye for an eye.

[ October 21, 2003, 12:47 AM: Message edited by: Schroeder ]

the_butcher · 10-21-2003, 02:51 AM

1. Talking with you about religion is a waste of time because you are so far fucking lost in your beliefs, so I don't want to get into it.

2. Everything was.

3. He did, however, he didn't say "if you bitch, then I'm going to bitch back". You're taking a concept of physical pain and trying to use it in a conversation of humility. Pathetic attempt you shit.

4. I hope you die and rot in the ground very soon. And I plan to help you out with that when we box. Speaking of which, when is that going to be, fucker?

[ October 21, 2003, 12:52 AM: Message edited by: the_butcher ]

Pliedes · 10-21-2003, 03:05 AM

Quote:

Originally posted by the_butcher:
turn the other cheek.

Quote:

Originally posted by Schroeder:
God also said an eye for an eye.

You're both offering incorrect interpretations of scripture. If you really want to get into it, sit down me sometimes and we'll have a real discussion. I'm serious.

People spend to much time arguing over things they can't prove, and not enough to time living (and believing) their own beliefs.

[ October 21, 2003, 01:05 AM: Message edited by: Pliedes ]

the_butcher · 10-21-2003, 03:13 AM

I don't believe in that scripture at all. In fact, I don't believe in about 99% of scripture. I was just proving a fact that Schroeder isn't sticking to the beliefs he claims to follow so closely.

Schroeder · 10-21-2003, 03:24 AM

Pliedes, no offense, but if I wanted to talk Scripture, I'd get the hell off of Nubblies.

Butcher, what do you believe?

Alpha · 10-21-2003, 08:29 AM

Quote:

Originally posted by Schroeder:
Pliedes, no offense, but if I wanted to talk Scripture, I'd get the hell off of Nubblies.

Could you? It'd be fantastic for the group's morale.

Titan · 10-21-2003, 09:20 AM

Quote:

Originally posted by Schroeder:
God also said an eye for an eye.

No offense Schroeder, but your god reminds me of a 2nd grader.

[ October 21, 2003, 07:20 AM: Message edited by: Titan ]

Combat Chuck · 10-21-2003, 01:51 PM

There goes Titan, thinking about 2nd graders again....

Trout Sniffer · 10-21-2003, 02:13 PM

To get back on the subject, I know tons of people that have taken Coricidin and it is fucking stupid. It's actually more harmful than "robo-tripping" because Robotussin is almost all DXM while Coricidin has other drugs in it, which are deadly at high doses.

The girls taking the drugs are fucking stupid, and I do think some of them are taking it partly for the popularity factor, that's how stupid some of them are. Of course it's also to get high, but I'm pretty sure they're doing it because it's "cool" too.

Saint DH · 10-21-2003, 02:50 PM

Well I bet we'll all have a nice long laugh when they're brain damaged!

Osiris · 10-21-2003, 03:21 PM

Just start selling placebo's to all the stupid girls and see how they react.

Pliedes · 10-21-2003, 03:26 PM

Quote:

Originally posted by Schroeder:
Pliedes, no offense, but if I wanted to talk Scripture, I'd get the hell off of Nubblies.

Which is exactly why I said I'd sit down and talk with you about it. Did you not read my post?

Quote:

Originally posted by Schroeder:

Butcher, what do you believe?

He, or anyone else, has no obligation, let alone a compelling reason, to discuss his beliefs with you.

StabMaster Arson · 10-21-2003, 03:45 PM

my god could beat up your god.

Osiris · 10-21-2003, 04:02 PM

"I don't hate the God, just your god." -Maynard

10-19-2003, 12:05 AM	#1 (permalink)
ProfessorNumber Senior Member Join Date: May 2003 Posts: 1,215 Internets: 3373	DXM, Coricidin, Robo-trippin, whatever you want to call it, is quite possibly the STUPIDEST drug of all times. I’ve noticed that the dangers of most drugs are over exaggerated, but when someone tells you that coricidin fries your brain, they aren’t kidding. You want to know what dissociatives such as DXM do to your brain? 1. Dissociatives activate neurons in the posterior cingulate cortex (PC) and retrosplenial cortex (RC). These overactive neurons pass along their excitation to "downstream" areas such as the hippocampus and olfactory areas. There are two theories on why the PC and RC neurons get overexcited in the first place; either one, both, or neither could be true. One theory is that NMDA receptors are found on inhibitory GABA interneurons, and that when these receptors are blocked, these interneurons secrete less GABA, and thus excitatory pyramidal neurons that normally receive a lot of GABA inhibition are overexcited. The other theory is that the PC and RC are less affected by NMDA blockade than the hippocampus (and related areas), and that these formations serve as feedback to the hippocampus and surrounding networks. As these limbic networks are inhibited, the PC and RC increase their output to compensate, resulting in overactivity. 2. The overactive cells begin to heat up, use up their energy supply generate toxic waste products, and/or let in too many calcium ions. 3. Regardless of the mechanism, or whether the mechanism is none of the above, the overactivity seems to cause intracellular organelles (notably mitochondria and endoplasmic reticulum) to malfunction. 4. The mitochondria probably lose their proton gradient and allow their innards to spill into the surrounding cell material, where they cause all sorts of trouble, possibly including forming free radicals which cause further damage to the cell. Another possibility is that the free radicals come first, and they cause damage to the mitochondria and other organelles. Mitochondrial damage can occur within 15 minutes of the drug dose, the endoplasmic reticulum is damaged 30 minutes, and in both cases gets worse as time progresses. The free radicals, basically, destroy everything in the cell like a rampant two-year-old on a spending spree through Toys-R-Us. 5. The cell responds to this damage with a protein called HSP70. This "heat shock" protein is made and activated when something (such as overheating, thus the name "heat shock protein" or HSP) is causing a cell to malfunction so badly as to be in danger of self-destructing, and its job is to turn the cell off until repairs can be made. Hopefully, the cell will get a lot of rest (about 24 hours) until it goes back to normal. At this point the problem is still reversible and the brain cells have not been permanently damaged. 6. If the cell continues to be overexcited, it eventually burns out completely as the increased temperature, disrupted ion gradient, hypoxia, calcium ions, free radicals, and/or buildup of waste products kill it. At this point, surrounding support cells called microglia are activated and come in and eat the cell (probably under the theory that if an infectious organism caused the cell death, it'd better be destroyed before the infection can spread). Source For those of you who are too lazy to read that, it basically states that damage is done to your brain when certain cells overheat and rupture. Taking excessive doses of dissociatives make certain parts of your brain fry like the proverbial egg-on-the-frying-pan in the "This is Your Brain on Drugs" commercial. Now, why is this relevant? Before I left Warsaw, I noticed that this “drug” was gaining a lot of popularity among stupid bitches. Why? Because of it’s easy availability, and quasi-legality. Personally I think it’s ridiculous that anyone would be so desperate to get “high” that they would stoop to using a fucking stupid drug like DXM. If you ever see someone using DXM/Coricidin, smack them on their fucking face.
	Smoke a cigarette and lie some more -- These conversations kill.

10-19-2003, 12:44 AM	#3 (permalink)
VOL Senior Member Join Date: Aug 2003 Location: there Posts: 2,305 Internets: -205	This drug is stupid and these girls taking it are probably only doing it for popularity. Same reason they all chew tabacco. It's just to say, "hey I'm doing a drug."
	~ductor ab grandis divinitus~ CDXXVII

10-19-2003, 01:14 PM	#5 (permalink)
VOL Senior Member Join Date: Aug 2003 Location: there Posts: 2,305 Internets: -205	I might have missed it. Does this drug (triple c) give the user a high. I mean what is the whole big thing. I was talking with a girl the other day who said that her and her friends took them. And they felt "good." What does that mean? Does this drug take immediate effect on the brain?
	~ductor ab grandis divinitus~ CDXXVII

10-19-2003, 02:08 PM	#6 (permalink)
Alpha Senior Member Join Date: May 2003 Posts: 1,003 Internets: 82	PN, your wisdom finally shows it's glory. Fuck all the stupid girls that do this, and all the guys for that matter.
	Gods are but men with immortal souls.

10-19-2003, 10:43 PM	#7 (permalink)
Niger Angelus We still believe. Join Date: Oct 2002 Location: Indiana Posts: 4,697 Internets: 216	I know a few girls that do it, one has quite the 'chunny fin', and yes; from what I have seen of them it does harm your brain.
	I enjoy knives and fire.

10-19-2003, 12:30 AM	#2 (permalink)
Schroeder Unwanted Join Date: Aug 2003 Posts: 1,543 Internets: -885	Ooh, a chance to go role reversal. Dear ProfessorNumber, Why do you try to push your ideals on others? Why don't you just let people do what they want? I mean, they are not hurting anyone but themselves. If they want to make themselves retarded, let them. I mean sometimes DXM is probably even helpful. If you had a brain tumor you could use DXM to kill the tumor. Yeah, DXM needs to be legalized more!

10-19-2003, 04:06 AM	#4 (permalink)
Saint DH Senior Member Join Date: Feb 2002 Posts: 6,147 Internets: 284753	Yeah, alot of people at the highschool do that all the time now it seems. The only problem is, I don't even think the stupid bitches know that the drug they are doing is called DXM. They call it "Triple C's" because the name of the pills they take are called Coricidin Cold and Cough. Those people that do this drug, do it quite often, and they're going to have some serious brain damage. I find it somewhat funny that people are so stupid as to take drugs that they really don't know anything about. If I was ever going to do a certain type of drug, I would research the fuck out of it, find out all the possible side effects, and possible things that could happen to me while on the drug. For instance, Coricidin can be lethal to certain types of people if they take too many of them...like the ammount that it would take to get fucked up off of them. Man people are fucking stupid. [ October 19, 2003, 02:08 AM: Message edited by: Dirty Harry ]

10-21-2003, 12:22 AM	#8 (permalink)
VOL Senior Member Join Date: Aug 2003 Location: there Posts: 2,305 Internets: -205	Niger, VOL knows these girls as well
	~ductor ab grandis divinitus~ CDXXVII

10-21-2003, 01:58 AM	#9 (permalink)
the_butcher Senior Member Join Date: Apr 2003 Location: ::: the recesses of my mind ::: Posts: 1,023 Internets: 10	First of all, Schroeder, fuck you. You try to push your god-fearing, Jesus-loving bullshit on us all the time. Don't try to talk about pushing ideals on people you fucking hypocrite. Second of all, VOL, they are taking the drug for popularity? Get your head out of your ass. Lastly, I know people who have done this many a time and not been affected mentally. While I have never done it myself, I see no harm in letting other people do it. However, I wouldn't trust pills that I didn't know what's in them. As for funny chin and her friends, fuck all those girls. They'd smoke cat shit if they thought it would get them high.
	\| bite the bullet and swallow lead \|

10-21-2003, 02:08 AM	#10 (permalink)
Schroeder Unwanted Join Date: Aug 2003 Posts: 1,543 Internets: -885	Tsk, tsk, Butcher. All I did was the same thing everyone always does to me.

10-21-2003, 02:40 AM	#11 (permalink)
the_butcher Senior Member Join Date: Apr 2003 Location: ::: the recesses of my mind ::: Posts: 1,023 Internets: 10	So you took a first grade mentality, congratulations. If he punches me, I'll punch him back. Are you sure that's the way Jesus would want you to handle things? If I can remember right, he once said to turn the other cheek. What's that? Suprised I know some scripture? Yeh, I was forced to waste a lot of time with it during childhood, but being the intelligent human being I am, I grew up and realized how much of a waste it was. Maybe someday you will to. Then again, probably not.
	\| bite the bullet and swallow lead \|

10-21-2003, 02:45 AM	#12 (permalink)
Schroeder Unwanted Join Date: Aug 2003 Posts: 1,543 Internets: -885	Am I really wasting my time? If I do just die and rot in the ground, has having a religion really cost me anything? No, Butcher, it has not. Not a single thing. If I do end up being right, well then, things will be great. I've got nothing to lose, and everything to gain. Sounds pretty intelligent to me. What about religion was a waste to you? God also said an eye for an eye. [ October 21, 2003, 12:47 AM: Message edited by: Schroeder ]

10-21-2003, 02:51 AM	#13 (permalink)
the_butcher Senior Member Join Date: Apr 2003 Location: ::: the recesses of my mind ::: Posts: 1,023 Internets: 10	1. Talking with you about religion is a waste of time because you are so far fucking lost in your beliefs, so I don't want to get into it. 2. Everything was. 3. He did, however, he didn't say "if you bitch, then I'm going to bitch back". You're taking a concept of physical pain and trying to use it in a conversation of humility. Pathetic attempt you shit. 4. I hope you die and rot in the ground very soon. And I plan to help you out with that when we box. Speaking of which, when is that going to be, fucker? [ October 21, 2003, 12:52 AM: Message edited by: the_butcher ]
	\| bite the bullet and swallow lead \|

10-21-2003, 03:13 AM	#15 (permalink)
the_butcher Senior Member Join Date: Apr 2003 Location: ::: the recesses of my mind ::: Posts: 1,023 Internets: 10	I don't believe in that scripture at all. In fact, I don't believe in about 99% of scripture. I was just proving a fact that Schroeder isn't sticking to the beliefs he claims to follow so closely.
	\| bite the bullet and swallow lead \|

10-21-2003, 03:24 AM	#16 (permalink)
Schroeder Unwanted Join Date: Aug 2003 Posts: 1,543 Internets: -885	Pliedes, no offense, but if I wanted to talk Scripture, I'd get the hell off of Nubblies. Butcher, what do you believe?

10-21-2003, 01:51 PM	#19 (permalink)
Combat Chuck Senior Member Join Date: Oct 2002 Posts: 2,063 Internets: 10	There goes Titan, thinking about 2nd graders again....

10-21-2003, 02:13 PM	#20 (permalink)
Trout Sniffer Senior Member Join Date: Oct 2002 Location: Straight Outta Compton Posts: 1,003 Internets: 123	To get back on the subject, I know tons of people that have taken Coricidin and it is fucking stupid. It's actually more harmful than "robo-tripping" because Robotussin is almost all DXM while Coricidin has other drugs in it, which are deadly at high doses. The girls taking the drugs are fucking stupid, and I do think some of them are taking it partly for the popularity factor, that's how stupid some of them are. Of course it's also to get high, but I'm pretty sure they're doing it because it's "cool" too.
	The Glyde don't sign no autographs

10-21-2003, 02:50 PM	#21 (permalink)
Saint DH Senior Member Join Date: Feb 2002 Posts: 6,147 Internets: 284753	Well I bet we'll all have a nice long laugh when they're brain damaged!

10-21-2003, 03:21 PM	#22 (permalink)
Osiris Senior Member Join Date: Sep 2003 Posts: 205 Internets: 10	Just start selling placebo's to all the stupid girls and see how they react.

10-21-2003, 03:45 PM	#24 (permalink)
StabMaster Arson Roscoe P. Coldchain Join Date: Feb 2002 Location: Stabbin Cabin Posts: 2,759 Internets: 1425	my god could beat up your god.
	LEGALIZE CRIME!

10-21-2003, 04:02 PM	#25 (permalink)
Osiris Senior Member Join Date: Sep 2003 Posts: 205 Internets: 10	"I don't hate the God, just your god." -Maynard