Sometimes watching O'Reily is difficult because he constantly interrupts his guests and shit. I feel like he did make some good points. Those billboards aren't going to help the atheists' cause at all, and it might actually hurt it. Many religious people will see those signs as an insult, and only turn them more toward religion. I think there are better messages that could be sent to further their cause.
With that thought, I'd like to leave you with this gem.