Top 10 Mad Scientists in History
http://www.oddee.com/item_96484.aspx
The list is good but gets kinda weak toward the end.
I would say the most fucked up one is
Sergei Bruyukhonenko: The Dog Decapitator
Way before Vladimir Demikhov, Bruyukhonenko's mad experiments on dogs led to the development of open-heart procedures. He developed a crude machine called the autojektor (a heart and lung machine). By using this primitive machine, Bryukhonenko kept the heads of severed dogs alive. In 1928, he displayed one of the heads in front of an audience. To prove it was real, he banged a hammer on the table. The head flinched. When a light was shone in its eyes, the eyes blinked. And when it was fed a piece of cheese, the remnants promptly popped out of the esophageal tube, much to the displeasure of disgusted viewers.
Here is the video. Its fucking graphic and I have no idea how its still on youtube.